Image by Esteban Lopez

Importers and Exporters of Premium Cannabis & Cannabis Based Products



Understanding THC


THC is metabolized mainly to 11-OH-THC by the body. This metabolite is still psychoactive and is further oxidized to 11-nor-9-carboxy-THC (THC-COOH). In humans and animals, more than 100 metabolites could be identified, but 11-OH-THC and THC-COOH are the dominating metabolites.[27]Metabolism occurs mainly in the liver by cytochrome P450 enzymes CYP2C9CYP2C19, and CYP3A4.[28] More than 55% of THC is excreted in the feces and ≈20% in the urine. The main metabolite in urine is the ester of glucuronic acid and THC-COOH and free THC-COOH. In the feces, mainly 11-OH-THC was detected.[29]

Learn More


Understanding CBD


Cannabidiol has low affinity for the cannabinoid CB1 and CB2 receptors,[31][32] although it can act as an antagonist of CB1/CB2 agonists despite this low affinity.[32] Cannabidiol may be an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain.[33] It also may act as an inverse agonist of GPR3GPR6, and GPR12.[34] CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist.[35] It is an allosteric modulator of the μ- and δ-opioid receptors as well.[36] The pharmacological effects of CBD may involve PPARγ agonism and intracellular calcium release.[7]

Learn More
CBD Molecular Structure.png

Let us provide our trade fulfilment expertise to connect the dots confidently

Crossing the T's and dotting each "i"

Join our network of service providers and public suppliers